Necrostatin-1 protects C2C12 myotubes from CoCl2-induced hypoxia
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چکیده
منابع مشابه
Necrostatin-1 protects C2C12 myotubes from CoCl2-induced hypoxia
Necrostatin-1 (Nec-1) is a selective and potent allosteric inhibitor of necroptosis by specifically inhibiting the activity of receptor‑interacting protein (RIP) 1 kinase. The aim of the present study was to determine the effect of Nec‑1 on an anoxia model comprising mouse skeletal C2C12 myotubes. In the present study, a hypoxic mimetic reagent, cobalt chloride (CoCl2), was used to induce hypox...
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ژورنال
عنوان ژورنال: International Journal of Molecular Medicine
سال: 2018
ISSN: 1107-3756,1791-244X
DOI: 10.3892/ijmm.2018.3466